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Center for Cancer Genomics and Personalized Medicine

Specialized medical services

NONOMURA Norio Director of Center for Developmental Medicine and Child Psychiatry

NONOMURA Norio
Director of
Center for Cancer Genomics and
Personalized Medicine

Cancer is fundamentally a disease of the genes (genome). As normal cells accumulate damaged genes (genome), they become malignant and turn into cancer. However, even in the same type of cancer, the acquired genetic changes (called “somatic genetic alterations”) that occur in cancer varies from patient to patient. At the Center for Cancer Genomics and Personalized Medicine, we investigate genes involved in cancer, especially genes that become therapeutic targets (cancer gene panel examination), and provide information to help select anticancer drugs (especially molecular target drugs). That is, we examine the genomic information of the patient’s cancer, and conduct an investigation that will lead to a highly effective “Cancer Genomic Medicine”.
In cases where a genetic abnormality is found as a target for treatment, if treatment of the patient’s cancer is covered by insurance, it may be done as ordinary health insurance treatment after confirmation by the existing examination. In addition, we inform patients about sponsor initiated clinical trials, investigator initiated clinical trials and other clinical trials in which they might become subjects. Patients who can participate in a trial might be able to receive medication that is not yet approved to treat the cancer with health insurance.
However, please understand that the percentage of genetic abnormalities that become targets for such treatment is not necessarily high at present.

Features

Osaka University Hospital was designated a Cancer Genome Core Hospital in February, 2018. We will promote cancer genomic medicine together with cancer genome collaboration hospitals. We analyze cancer gene panel examinations at the quality assurance genetics laboratory on the 5th floor of the Oncology Center. All of the processes of the examination are done in the hospital, so the examination can be undertaken with confidence.
In addition, our quality assurance genetics laboratory has received accreditation (CAP-LAP) by the College of American Pathologists.

Notice: Designation as Cancer Genome Core Hospital (Japanese only)

Considerations in referring your patients to our hospital

Our medical examination and tests are not covered by insurance. They are not offered as private practice either by Osaka University Hospital, in which patients bear their own medical expenses.
On October 1, 2018, we began to provide cancer gene panel examinations in the Advanced Medical Care B program. Patients who wish to be examined should consult with their doctor, and obtain a referral from the doctor to the clinical department at Osaka University Hospital.
Although the costs of advanced medical treatment are borne by the patient, unlike private practice, public health insurance can cover the costs of examination, medication and hospitalization.

On the procedures for referrals and making appointments

Our Social Service Department accepts appointments through regional medical facilities.

Referral/Appointment Procedures (Japanese only)

Documents to be given to the patient to bring when visiting our hospital

  1. Medical appointment form / Treatment application form
  2. Letter of referral (providing medical information) [prepared by the regional medical facility]
  3. Clinical information entry form for the multiplex gene panel examination [prepared by the regional medical facility: please fill out the prescribed form]

    Form 1 “Multiplex Gene Panel Examination Clinical Information Entry Form”
    PDF  Excel
  4. Report of pathological diagnosis [prepared by the regional medical facility]
  5. Formalin-fixed paraffin block [1 representative block including the main lesion: sufficient residual tissue is desirable]
  6. Specimen information form for the multiplex gene panel examination [prepared by the regional medical facility: please fill out the prescribed form]

    Form 2 “Multiplex Gene Panel Examination Specimen Information Form”
    PDF  Excel

Cost of the examination

The cost to patient is about ¥245,000. (With Osaka University Hospital bearing a further ¥200,000, the total cost of the examination is about ¥445,000.)
The examination may not be successful depending on the quality (due to collection method, fixing conditions, etc.) or the quantity of the tissue sample. In such a case, the costs are still incurred. Please take this into account.

Eligibility criteria

  1. Pathologically diagnosed as solid cancer (excluding hematological tumors or sarcomas)
  2. Having inoperable Stage III/IV or advanced/recurrent refractory cancer (with no standard treatment, or standard treatment terminated or expected to be terminated)
  3. Age 16 years or older
  4. Overall condition is satisfactory
  5. Initial effect of standard drug therapy can be determined
  6. A surplus sample can be obtained as a cancer tissue sample for the gene panel examination

Press Release: Osaka University Hospital implements cancer genomics as “advanced medical treatment”

If you have any questions, please contact the Center for Cancer Genomics and Personalized Medicine at [contact * mccg.med.osaka-u.ac.jp]. Replace * with @.

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Guide for Visitors
Outpatient consultation days
Monday to Friday
Non-consultation days
Saturdays, Sundays, Holidays
New Year’s Holidays:
Dec. 29 to Jan. 3
Consultation times
First visit: 8:30 am to 11:00 am

First-time visitors to Osaka University Hospital must have a referral from a physician.

Revisit: 8:30 am to 11:30 am
Revisit with appointment: 8:30 am to 3:00 pm

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We cannot answer questions about diseases or treatments by telephone or mail. Please ask in consultation at the hospital.